We revisit the case for the hyperthermophilic scenario for the origin of life and the last common ancestor. Evidence includes studies of phylogenetic trees, rRNA, G and C content, hyperthermophilic proteins, correlations between maximal temperature tolerances and genetic distances, saline stabilization of DNA/RNA, and the inferred climatic temperatures of the early Earth. Although some doubts remain, the case for hot biogenesis and the last common ancestor has gotten stronger.
- last common ancestor (LCA)
- reverse gyrase
Thermophiles 2003, a held at University of Exeter, 15–19 September 2003
Abbreviation used: LCA, last common ancestor.
- © 2004 Biochemical Society