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Issues
April 2016
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Cover Image
Cover Image
Endoplasmic reticulumendosome contact sites. This pseudo-colored electron microscopy image shows the formation of inter-organelle membrane contact sites between late endosomes (magenta) and the endoplasmic reticulum (ER; green). This tethering results from the interaction between two ER-anchored proteins (VAP-A and VAP-B) and the late endosomeanchored protein STARD3NL. Mitochondria: brown; nucleus: blue. For further details see pp. 493-498. Image kindly provided by Fabien Alpy. - PDF Icon PDF LinkTable of Contents
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Biochemical Society Focused Meetings
Chimeric Antigen Receptor Therapy in Haematology and Oncology: Current Successes and Challenges
Antigen-specificity using chimeric antigen receptors: the future of regulatory T-cell therapy?
Biochem Soc Trans (2016) 44 (2): 342–348.
Homing to solid cancers: a vascular checkpoint in adoptive cell therapy using CAR T-cells
Biochem Soc Trans (2016) 44 (2): 377–385.
Targeting the tumour profile using broad spectrum chimaeric antigen receptor T-cells
Biochem Soc Trans (2016) 44 (2): 391–396.
Efficacy and toxicity management of CAR-T-cell immunotherapy: a matter of responsiveness control or tumour-specificity?
Biochem Soc Trans (2016) 44 (2): 406–411.
Armored CAR T-cells: utilizing cytokines and pro-inflammatory ligands to enhance CAR T-cell anti-tumour efficacy
Biochem Soc Trans (2016) 44 (2): 412–418.
Organelle Crosstalk in Membrane Dynamics and Cell Signalling
ER–endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans (2016) 44 (2): 441–446.
The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites
Biochem Soc Trans (2016) 44 (2): 447–451.
Regulation of calcium and phosphoinositides at endoplasmic reticulum–membrane junctions
Biochem Soc Trans (2016) 44 (2): 467–473.
Structural comparison of yeast and human intra-mitochondrial lipid transport systems
Biochem Soc Trans (2016) 44 (2): 479–485.
When under pressure, get closer: PERKing up membrane contact sites during ER stress
Biochem Soc Trans (2016) 44 (2): 499–504.
Roles for Ca2+ mobilization and its regulation in mast cell functions: recent progress
Biochem Soc Trans (2016) 44 (2): 505–509.
Lipid transfer proteins do their thing anchored at membrane contact sites… but what is their thing?
Biochem Soc Trans (2016) 44 (2): 517–527.
Vacuole membrane contact sites and domains: emerging hubs to coordinate organelle function with cellular metabolism
Biochem Soc Trans (2016) 44 (2): 528–533.
Mitophagy as a stress response in mammalian cells and in respiring S. cerevisiae
Biochem Soc Trans (2016) 44 (2): 541–545.
GPCRs: Beyond Structure Towards Therapy
From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins
Biochem Soc Trans (2016) 44 (2): 555–561.
Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins
Debbie L. Hay; Christopher S. Walker; Joseph J. Gingell; Graham Ladds; Christopher A. Reynolds; David R. Poyner
Biochem Soc Trans (2016) 44 (2): 568–573.
Using the fragment molecular orbital method to investigate agonist–orexin-2 receptor interactions
Alexander Heifetz; Matteo Aldeghi; Ewa I. Chudyk; Dmitri G. Fedorov; Mike J. Bodkin; Philip C. Biggin
Biochem Soc Trans (2016) 44 (2): 574–581.
The complexity of signalling mediated by the glucagon-like peptide-1 receptor
Biochem Soc Trans (2016) 44 (2): 582–588.
Variants of G protein-coupled receptors: a reappraisal of their role in receptor regulation
Roberto Maggio; Irene Fasciani; Mario Rossi; Jacopo Di Gregorio; Ilaria Pietrantoni; Valentina Puca; Vincenzo Flati; Marco Scarselli
Biochem Soc Trans (2016) 44 (2): 589–594.
Evidence for the heterotetrameric structure of the adenosine A2A–dopamine D2 receptor complex
Verònica Casadó-Anguera; Jordi Bonaventura; Estefanía Moreno; Gemma Navarro; Antoni Cortés; Sergi Ferré; Vicent Casadó
Biochem Soc Trans (2016) 44 (2): 595–600.
Proteinase-activated receptors (PARs) as targets for antiplatelet therapy
Biochem Soc Trans (2016) 44 (2): 606–612.
Structure network analysis to gain insights into GPCR function
Biochem Soc Trans (2016) 44 (2): 613–618.
GPCR–styrene maleic acid lipid particles (GPCR–SMALPs): their nature and potential
Mark Wheatley; Jack Charlton; Mohammed Jamshad; Sarah J. Routledge; Sian Bailey; Penelope J. La-Borde; Maria T. Azam; Richard T. Logan; Roslyn M. Bill; Tim R. Dafforn; David R. Poyner
Biochem Soc Trans (2016) 44 (2): 619–623.
The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors
Biochem Soc Trans (2016) 44 (2): 624–629.
Independent Meetings
5th European Lipidomic Meeting
When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite1
Biochem Soc Trans (2016) 44 (2): 631–637.
Mass spectrometry and its evolving role in assessing tissue specific steroid metabolism
Biochem Soc Trans (2016) 44 (2): 645–651.
Biochemical Society Awards
The Thudichum Medal Lecture presented by Professor John Hardy
Catastrophic cliffs: a partial suggestion for selective vulnerability in neurodegenerative diseases
Biochem Soc Trans (2016) 44 (2): 659–661.
Corrections
Correction: Learning from each other: ABC transporter regulation by protein phosphorylation in plant and mammalian systems
Biochem Soc Trans (2016) 44 (2): 663–673.
