Table 2 Thiol oxidation and thiol antioxidants in oxidative stress and redox regulation

NAC, N-acetylcysteine; Grx, glutaredoxin.

Oxidative stressRedox regulation
Protein thiol oxidationDamageRegulation
Oxidants‘Evil’ moleculesNeither good nor bad
Thiol antioxidants (e.g. GSH, NAC, Grx)Free radical scavengers and antioxidantsReducing agents